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产品介绍
AdTx1 (rho-Da1a – ρ-Da1b)
Selective antagonist of the alpha(1A)-adrenoceptor
肾上腺受体alpha(1A)选择性拮抗剂
AdTx1 (rho-Da1a – ρ-Da1b) is a 65 amino-acid peptide originally isolated from the venom of the green mamba, an African snake (Dendroaspis angusticep). AdTx1 is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. AdTx1 has subnanomolar affinity (K(i)= 0.35 nM) and high specificity for the human alpha(1A)-adrenoceptor subtype and is 1000 times more potent on this subtype than on other adrenoceptor subtypes. AdTx1is a potent relaxant of smooth muscles.
AdTx1 (rho-Da1a – ρ-Da1b)技术资料
氨基酸序列:
LTC3VTSKSIFGITTEDC17PDGQNLC24FKRRHYVVPKIYDSTRGC42AATC46PIPENYDSIHC57C58KTDKC63NE
二硫键: Cys3-Cys24, Cys17-Cys42, Cys46-Cys57, Cys58-Cys63
长度 (aa): 65
分子式:C310H481N87O100S8
分子量(平均):7283.29 Da
外观:White lyophilized solid
可溶性:water and saline buffer
CAS 号:not available
来源:Synthetic
纯度:> 98%
产品信息
货号 | 名称 | 规格 |
ADT001-00010 | AdTx1 (rho-Da1a – ρ-Da1b) | 10ug/5×10ug |
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