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产品介绍
Waglerin-1-FAM (羧基荧光素标记的Waglerin-1)
Waglerin-1 blocks muscle nAChRs
阻断肌肉乙酰胆碱受体
Waglerin-1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler’s pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of adult muscle nicotinic acetylcholine receptors. Waglerin-1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin-1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin-1 are currently used in cosmetics to reduce wrinkles. The fluorescent derivative Waglerin-1-FAM can be use to explore the expression and function of the adult nAChR subtypes.
Waglerin-1-FAM技术资料
氨基酸序列:
FAM-Gly-Gly-Lys-Pro-Asp-Leu-Arg-Pro-Cys9-His-Pro-Pro-Cys13-His-Tyr-Ile-Pro-Arg-Pro-Lys-Pro-Arg-OH
二硫键: Cys9-Cys13
长度 (aa): 22
分子式:C133H185N37O32S2
分子量:2878.27 Da
CAS 号:NA
来源:Synthetic
荧光染料:FAM, 5(6)-carboxyfluorescein (λex 492, λem 517)
产品信息
货号 | 名称 | 规格 |
WAG002-00100 | Waglerin-1-FAM (羧基荧光素标记的Waglerin-1) | 100ug/500ug/1000ug |
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